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screw up

verb

1.

make more intense

2.

make a mess of, destroy or ruin

ball up blow bobble bodge bollix bollix up bollocks bollocks up botch botch up bumble bungle flub fluff foul up fuck up fumble louse up mess up mishandle muck up muff spoil

Derived from:

3.

screw or turn higher

4.

twist into a strained configuration