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nub
noun
1.
a small lump or protuberance
knottle
nubble
Derived from:
nubby
2.
a small piece
stub
3.
the choicest or most essential or most vital part of some idea or experience
colk
hirnstone
inmost
innermost
kernling
center
centre
core
essence
gist
heart
heart and soul
inwardness
kernel
marrow
meat
nitty-gritty
pith
substance
sum