isolation
noun
1.
a state of separation between persons or groups
Derived from:
isolate 2.
a feeling of being disliked and alone
3.
the act of isolating something; setting something apart from others
4.
(psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it
Derived from:
isolate 5.
a country's withdrawal from international politics