impairment

noun

1.
the occurrence of a change for the worse
Derived from:
impair
2.
a symptom of reduced quality or strength
3.
the condition of being unable to perform as a consequence of physical or mental unfitness
4.
damage that results in a reduction of strength or quality
Derived from:
impair
5.
the act of making something futile and useless (as by routine)